GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7714584 | 1 | rs6862814 | chr5:150245259 | LOC134466 | chr5:150310000-150326146:- | 0.38 | 5.36 | 1.31E-7 | Crohn's disease |
| THCA | cis | rs6878284 | 1 | rs6863068 | chr5:101769728 | SLCO4C1 | chr5:101569694-101632253:- | 0.24 | 5.49 | 6.41E-8 | Schizophrenia |
| THCA | cis | rs515910 | 1 | rs686441 | chr10:105950233 | C10orf79 | chr10:105889647-105992120:- | 0.24 | 7.65 | 1.15E-13 | Attention deficit hyperactivity disorder |
| THCA | cis | rs6878284 | 1 | rs6867264 | chr5:101693046 | SLCO4C1 | chr5:101569694-101632253:- | 0.25 | 5.62 | 3.21E-8 | Schizophrenia |
| THCA | cis | rs6878284 | 1 | rs6867496 | chr5:101770045 | SLCO4C1 | chr5:101569694-101632253:- | 0.24 | 5.54 | 5.1E-8 | Schizophrenia |
| THCA | cis | rs3853750 | 1 | rs6869502 | chr5:110166083 | TMEM232 | chr5:109624934-110062381:- | 0.21 | 4.23 | 2.85E-5 | Asthma and hay fever |
| THCA | cis | rs2416257 | 1 | rs6869774 | chr5:110467086 | TSLP | chr5:110405778-110413722:+ | -0.33 | -4.72 | 3.08E-6 | Eosinophil counts |
| THCA | cis | rs2416257 | 1 | rs6869774 | chr5:110467086 | WDR36 | chr5:110427870-110466201:+ | 0.19 | 3.75 | 0.000198 | Eosinophil counts |
| THCA | cis | rs1010254 | 1 | rs6870097 | chr5:151734471 | NMUR2 | chr5:151771102-151784840:- | -0.51 | -9.43 | 1.73E-19 | Optic nerve measurement (cup area) |
| THCA | cis | rs2416257 | 1 | rs6870356 | chr5:110467237 | TSLP | chr5:110405778-110413722:+ | -0.37 | -5.32 | 1.56E-7 | Eosinophil counts |
| THCA | cis | rs1010254 | 1 | rs6870816 | chr5:151734701 | NMUR2 | chr5:151771102-151784840:- | -0.51 | -9.43 | 1.73E-19 | Optic nerve measurement (cup area) |
| THCA | cis | rs6878284 | 1 | rs6872341 | chr5:101776535 | SLCO4C1 | chr5:101569694-101632253:- | 0.25 | 5.62 | 3.21E-8 | Schizophrenia |
| THCA | cis | rs6878284 | 1 | rs6873305 | chr5:101724307 | SLCO4C1 | chr5:101569694-101632253:- | 0.26 | 5.86 | 8.84E-9 | Schizophrenia |
| THCA | cis | rs7714584 | 1 | rs6874560 | chr5:150182713 | LOC134466 | chr5:150310000-150326146:- | 0.44 | 5.7 | 2.13E-8 | Crohn's disease |
| THCA | cis | rs7714584 | 1 | rs6874560 | chr5:150182713 | ZNF300 | chr5:150273964-150284391:- | 0.18 | 3.72 | 0.000222 | Crohn's disease |